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HPLC and UHPLC systems — selection and configuration

HPLC and UHPLC systems separate mixture components using a liquid mobile phase. Applications include pharmaceutical quality control, food testing, environmental monitoring and analytical chemistry.

Select equipment and request a quotation

State your method, workload and required options to prepare a comparable quotation.

Selecting a system

  • Pump pressure and flow range compatible with the columns and method.
  • Isocratic or gradient operation, binary or quaternary mixing.
  • Autosampler capacity and sample temperature control.
  • UV/VIS, diode-array, fluorescence or other compatible detectors.
  • Software and data processing requirements.

Modules, columns and consumables depend on the selected configuration. For volatile compounds, also explore gas chromatographs.

Compare three HPLC and UHPLC systems

ModelKey differences
Agilent 1260 Infinity III LCUp to 600 bar; modular HPLC platform for routine methods; pump and detector specified separately
Agilent 1260 Infinity III Prime LCUp to 800 bar; quaternary Flexible Pump; 0.001–5 mL/min; ISET and BlendAssist
Agilent 1290 Infinity III LCUp to 1300 bar; selected binary High-Speed Pump; 0.001–5 mL/min; DAD up to 240 Hz

Pressure and flow limits depend on the pump and operating mode and are not guaranteed simultaneously under all conditions. Specify the detector, autosampler, column compartment and InfinityLab Assist.

Request a price for the agreed configuration.

Manufacturer information and documents

Check the version, supply region and document revision. A series page may describe options that are not included in the specific configuration.

Configuration, pricing and procurement

For a quotation, specify the required configuration, number of instruments, installation city and services needed. Agree options, consumables, commissioning and staff familiarisation separately. Documentation, delivery times and warranty terms are specified in the quotation and contract. See the model page for its current price or quotation request option.

Questions before selection and procurement

Which models are listed?

Agilent 1260 Infinity III LC · Agilent 1260 Infinity III Prime LC · Agilent 1290 Infinity III LC.

How do Prime and 1290 differ?

Prime combines quaternary mixing with pressure up to 800 bar. The 1290 listing selects a binary High-Speed Pump for UHPLC up to 1300 bar; the quaternary Flexible Pump is an alternative configuration. Check method compatibility against the column, mobile phase, delay volume and detector.

What should be specified in the supply package?

Photographs illustrate multi-module systems. Injection volume, column capacity, sample cooling, detectors, software licences and Assist depend on the ordered equipment. Quotation requires the methods, sample throughput and exact module list.

How can a fixed price be obtained?

Agree the exact equipment and option list, installation, training and service. A fixed price is established for a confirmed specification; each product page provides a quotation request.

Related categories and support

Project support · Technical service